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Surrogate tissues for detecting brain microemboli after cardiopulmonary bypass

Departments of Radiology, Pathology and Program in Neuroscience, Bowman Gray School of Medicine of Wake Forest University

Dixon M Moody

Department of Radiology and Program in Neuroscience, Bowman Gray School of Medicine of Wake Forest University

Stephen A Mills

Department of Cardiothoracic Surgery Bowman Gray School Medicine of Wake Forest University

Randy L Anderson

Department of Public Health Sciences, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina

During cardiopulmonary bypass (CPB) microemboli lodge in the brain and other organs. Microemboli were counted in tissue samples of skin, muscle and brain from autopsy cases that had recently undergone CPB, and in skin and muscle biopsies obtained from patients before and after CPB. Unlike the brain, skin and muscle showed few microemboli.

Perfusion, Vol. 9, No. 6, 389-392 (1994)
DOI: 10.1177/026765919400900603


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