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Risk factors for renal dysfunction after coronary surgery: the role of cardiopulmonary bypass technique

Marco Ranucci

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Marco Pavesi

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Ermanno Mazza

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Carla Bertucci

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Alessandro Frigiola

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Lorenzo Menicanti

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

A. Ditta

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

A. Boncilli

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

Daniela Conti

Department of Cardiovascular Anaesthesiology, Department of Cardiac Surgery, and Department of Intensive Care Medicine, Cardiovascular Center E Malan, S Donato Hospital, University of Milan, Milan

We studied 316 patients undergoing cardiopulmonary bypass for coronary artery surgery in order to determine perioperative risk factors for postoperative renal dysfunction

A preliminary univariate analysis was performed by {chi}2 analysis for categorical data and Mann-Whitney U-test for continuous variables to detect significant correlations between each risk factor and the occurrence of moderate or severe renal dysfunction. Subsequently, a multiple logistic regression was applied to the three risk factors identified as predictive for severe renal dysfunction. Low cardiac output syndrome and need for banked blood transfusions combined with a low haematocrit value during cardiopulmonary bypass increase the probability of severe renal dysfunction in the postoperative course.

Perfusion, Vol. 9, No. 5, 319-326 (1994)
DOI: 10.1177/026765919400900503


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