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Perfusion
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Transient hypercoagulability in adult patients following open-heart surgery

F. Horkay

Cardiothoracic Unit, Killingbeck Hospital, Leeds

P. Martin

Cardiothoracic Unit, Killingbeck Hospital, Leeds

NK Gupta

Cardiothoracic Unit, Killingbeck Hospital, Leeds

Cmr Satur

Cardiothoracic Unit, Killingbeck Hospital, Leeds

DR Walker

Cardiothoracic Unit, Killingbeck Hospital, Leeds

The technique of thrombelastography was used to assess whether the phenomenon of hypercoagulability (accelerated coagulation) occurred in adult patients (n = 20) undergoing consecutive open-heart surgical procedures. Standard haematological investigations (pre- and 2 hours postop) were also performed and comparisons made with thrombelastographic parameters. Thrombelastographic hypercoagulability was identified in 12/20 (60%) cases but this event was transient occurring immediately postprotamine administration, and normalizing at 2h postoperation. The standard postoperative haematological assessments routinely made 2h after operation failed to detect this phenomenon. Hypercoagulability following cardiac surgery in adult patients merits further evaluation in order that the clinical significance may be determined.

Perfusion, Vol. 7, No. 2, 119-123 (1992)
DOI: 10.1177/026765919200700207
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