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Platelet consumption during neonatal extracorporeal life support (ECLS)

Franz B Plötz

Department of Pediatrics, Neonatology, University Hospital, Groningen, NL

Walter R Wildevuur

Department of Cardio-Pulmonary Surgery, Research Division, University Hospital, Groningen, The Netherlands

Charles RH Wildevuur

Department of Cardio-Pulmonary Surgery, Research Division, University Hospital, Groningen, The Netherlands

Ralph E Delius

Department of Surgery, University of Michigan Hospitals, Ann Arbor

Robert H Bartlett

Department of Surgery, University of Michigan Hospitals, Ann Arbor

This paper reports the results of a retrospective study of blood use and blood loss in 40 neonates during extracorporeal life support (ECLS). Immediately after onset of bypass 39±2.5ml platelets, 59.4±6.5ml packed red blood cells (PRBC) and 15.0±5.4ml fresh frozen plasma (FFP) per patient were needed. The average daily amount given per patient was 49.0±3.0ml of platelets and 48.0±3.4ml and 9.6±3.9ml of PRBC and FFP respectively. The 10 patients who had bleeding complications received 50.0±6.3ml/day of platelets compared to 49.0±3.4ml in the other patients. The majority of blood loss during the entire period of ECLS was from samples, averaging 43.0 ± 1.5ml/day. Neck wound drainage, 6.7±2.5ml/day per patient, lasted for the entire period.

Perfusion, Vol. 7, No. 1, 27-33 (1992)
DOI: 10.1177/026765919200700106
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