Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Perfusion
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Massaut, J.
Right arrow Articles by Vanderrieviere, J.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Massaut, J.
Right arrow Articles by Vanderrieviere, J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Changes in plasma leucocyte elastase levels during coronary surgery and effects of steroids and nifedipine infusion

J. Massaut

Department of Anaesthesiology, Brugmann Hospital, Brussels Free University

N. Hennebert

Department of Chemistry, Brugmann Hospital Brussels Free University

F. Deuvaert

Department of Cardiac Surgery, Brugmann Hospital, Brussels Free University

J. Vanderrieviere

Department of Perfusion Technology, Brugmann Hospital, Brussels Free University

Circulating concentrations of leucocyte elastase were measured in 20 adult patients undergoing cardiopulmonary bypass (CPB) with a flat-sheet membrane oxygenator. Eight patients (group I) received the calcium channel blocker, nifedipine (9µg/kg/h), during CPB and 2g methylprednisolone before CPB. Eight patients (group II) received methylprednisolone but not nifedipine infusion. Four patients (group III) received neither nifedipine nor methylprednisolone infusion. In all patients the bypass procedure was associated with elevation in elastase concentrations. Enzyme concentrations correlated with the duration of bypass (r = 0.7, p<0.01). Comparison between groups fails to demonstrate any significant effect of nifedipine infusion or methylprednisolone on elastase release. This study demonstrates moderate elastase release during CPB with a flat-sheet membrane oxygenator and fails to confirm inhibition of elastase release by nifedipine infusion during CPB.

Perfusion, Vol. 6, No. 4, 253-259 (1991)
DOI: 10.1177/026765919100600403
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 PerfusionHome page
D. A Palanzo, N. J Manley, R. M Montesano, G. L Yeisley, and D. Gordon
Clinical evaluation of the LeukoGuard (LG-6) arterial line filter for routine open-heart surgery
Perfusion, November 1, 1993; 8(6): 489 - 496.
[Abstract] [PDF]