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Perfusion
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Correlates of total perfusion time, clamp time and nonclamp perfusion time in coronary bypass surgery

Joe R Utley

University of South Carolina School of Medicine, Columbia, Division of Cardiac Surgery, Spartanburg Regional Medical Center, Spartanburg

Marc S Morgan

Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston

Howard D Johnson

Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston

Connie M Wilde

Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston

Michael S Bell

Division of Cardiothoracic Surgery, Medical University of South Carolina, Charleston

Longer perfusion and clamp times are associated with greater mortality and morbidity. We studied the factors which correlate with the duration of perfusion time, clamp time and nonclamp perfusion time in 1078 patients having coronary bypass surgery. Perfusion time correlated significantly (P≤ 0.05) with female sex, ejection fraction, left ventricular diastolic pressure, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta, aorto-iliac-femoral occlusive disease and date of operation. Only the number of distal anastomoses, incomplete revascularization, atherosclerotic aorta, ejection fraction and date of operation correlated significantly (P≤ 0.05) with perfusion time with multiple regression analysis. Factors significantly (P≤ 0.05) correlating with nonclamp perfusion time included age, ejection fraction, left ventricular end diastolic pressure, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta and aorto-iliac-femoral occlusive disease. Multiple regression analysis showed that only ejection fraction, number of distal anastomoses, incomplete revascularization and atherosclerotic aorta significantly (P≤ 0.05) contributed to the predication of nonclamp perfusion time. The individual correlates (P≤ 0.05) of clamp time included age (negative correlation), female sex, ejection fraction, height, weight, body surface area, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta and date of operation. Multiple regression analysis shows that clamp time correlates significantly (P ≤ 0.05) with the number of distal anastomoses, date of operation, age, incomplete revascularization, atherosclerotic aorta and female sex.

Perfusion, Vol. 4, No. 4, 265-273 (1989)
DOI: 10.1177/026765918900400404


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J. R Utley, S. A Leyland, H. D Johnson, M. S Morgan, C. M Wilde, M. S Bell, M. M Sawaf, and B. S Harrison
Correlation of preoperative factors, severity of disease, type of oxygenator and perfusion times with mortality and morbidity of coronary bypass
Perfusion, January 1, 1991; 6(1): 15 - 22.
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