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Perfusion
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research-article

New bench test for venous cannula performance assessment

S Abdel-Sayed

Department of Cardio-Vascular Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

J Favre

Laboratory for Movement Analysis and Measurement, Swiss Federal Institute of Technology, Lausanne, Switzerland

J Horisberger

Department of Cardio-Vascular Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

S Taub

Department of Cardio-Vascular Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

D Hayoz

Department of Internal Medicine, H�pital cantonal, Fribourg, Switzerland

LK von Segesser

Department of Cardio-Vascular Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

Cannula design is of prime importance for venous drainage during cardiopulmonary bypass (CPB). To evaluate cannulas intended for CPB, an in vitro circuit was set up with silicone tubing between the test cannula encased in a movable preload reservoir and another static reservoir. The pressure-drop ({Delta}P) value (P-drainage – P-preload) was measured using Millar pressure transducers. Flow rate (Q) was measured using an ultrasound flowmeter. Data display and data recording were controlled using a LabView application, custom made particularly for our experiments. Our results demonstrated that {Delta}P, Q, and cannula resistance ({Delta}P/Q) values were significantly decreased when the cannula diameter was increased for Smart and Medtronic cannulas. Smartcanula® showed 36% and 43% less resistance compared to Medtronic venous and Medtronic femoral cannulas, respectively. The cannula shape (straight- or curved-tips) did not affect the DLP cannula resistance. Out of five cannulas tested, the Smartcanula® outperforms the other commercially available cannulas. The mean ({Delta}P/Q) values were 3.3�±�0.08, 4.07�±�0.08, 5.58�±�0.10, 5.74�±�0.15, and 6.45�±�0.15 for Smart, Medtronic, Edwards, Sarns, and Gambro cannulas, respectively (two-way ANOVA, p < 0.0001). In conclusion, the present assay allows discrimination between different forms of cannula with high or low lumen resistance.

Key Words: Cardiopulmonary bypass • cannulas • venous drainage • flow rate • lumen resistance

Perfusion, Vol. 22, No. 6, 411-416 (2007)
DOI: 10.1177/0267659108089759
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