Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Perfusion
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by McCusker, K.
Right arrow Articles by Vijay, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCusker, K.
Right arrow Articles by Vijay, V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Influence of hematocrit and pump prime on cerebral oxygen saturation in on-pump coronary revascularization

Kevin McCusker

Portsmouth Regional Hospital, NH, USA

Anthony Chalafant

Northeastern University, Boston, MA, USA

Gordon de Foe

Dartmouth Medical Center, Lebanon, NH, USA

Serdar Gunaydin

University of K. Kale, Turkey, sgunaydin{at}isnet.net.tr

Venkataramana Vijay

Tarrytown, New York, USA

Background: The couplings between cerebral oxygenation (rSO2), on-pump hematocrit and circuit prime are explored in this study.

Methods: Thirty-eight consecutive patients undergoing coronary revascularization with cardiopulmonary bypass (CPB) were matched on preoperative hematocrit < 40% and >40% (n=16). Similarly, six blood prime patients were matched with six crystalloid prime patients. Hematocrit and rSO2 levels were then compared on CPB.

Results: The pre-operative hematocrit >40% group retained higher levels on pump run (p < 0.01) and significantly higher rSO2 prior to CPB (64.8±9.6 versus 73.2±7.3), and on and off CPB (61.1±8.8 versus 67.4±6.4). Blood priming increased absolute rSO2 (2.3± 6.3 versus – 10.9±5.9) and% rSO2 (4.7±11.8 versus –14.2±7.4%) in the low hematocrit group.

Conclusion: Blood primes are instrumental in high-risk and low preoperative hematocrit patients in preventing cerebral oxygen desaturation during initiation and maintenance of CPB.

Perfusion, Vol. 21, No. 3, 149-155 (2006)
DOI: 10.1191/0267659106pf863oa
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?