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Perfusion
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A low prime extracorporeal system for small patients: a primate model

D. Wheeldon

Papworth Hospital, Cambridge

D. Bethune

Papworth Hospital, Cambridge

In the course of developing a technique for heart and lung transplantation a 6 kg Rhesus monkey model was used. We required a low prime circuit, because it was difficult to obtain donor blood for these animals, which was also capable of supporting the circulation for up to two hours. We describe a system incorporating a semidisposable bubble oxygenator, run under controlled negative pressure with very short blood lines. This arrangement allows for a priming volume of 110 ml with good venous drainage control. The principle could be exploited for use with paediatric extracorporeal systems.

Perfusion, Vol. 2, No. 1, 35-38 (1987)
DOI: 10.1177/026765918700200106
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