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Pump-induced haemolysis: a comparison of short-term ventricular assist devices

M Bennett

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia, martin.bennett{at}rch.org.au

S Horton

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia

C Thuys

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia

S Augustin

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia

M Rosenberg

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia

C Brizard

Cardiac Surgical Unit, Royal Children’s Hospital, Parkville, Victoria, Australia

Centrifugal pumps are superior to roller pumps for extended support durations in terms of pump-induced haemolysis. In this study, we evaluated the commonly used Biomedicus BP 50 and compared it with the Jostra Rotaflow and a standard roller pump in an in vitro test circuit. Each circuit was run for a six-day period and repeated five times. Plasma haemoglobin values showed the roller pump to become more haemolytic than the Biomedicus (p = 0.022) and the Rotaflow. A statistically significant difference between the Biomedicus and the Rotaflow was observed on day six of the trial (p = 0.016), with the Rotaflow showing lower levels of haemolysis than the Biomedicus. These results support the use of the new generation centrifugal pump, the Rotaflow, as a suitable device for short-term ventricular assist.

Perfusion, Vol. 19, No. 2, 107-111 (2004)
DOI: 10.1191/0267659104pf729oa
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A.P.S. Thiara, T.N. Hoel, F. Kristiansen, H.M. Karlsen, A.E. Fiane, and J.L. Svennevig
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[Abstract] [PDF]