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Safe minimization of cardiopulmonary bypass circuit volume for complex cardiac surgery in a 3.7 kg neonate

Wolfgang Boettcher

Department of Perfusion, Deutsches Herzzentrum Berlin, Germany

Frank Merkle

Department of Perfusion, Deutsches Herzzentrum Berlin, Germany

Andreas Koster

Department of Anesthesia, Deutsches Herzzentrum Berlin, Germany, koster{at}dhzb.de

Michael Hübler

Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany

Brigitte Stiller

Department of Congenital Heart Disease, Deutsches Herzzentrum Berlin, Germany

Hermann Kuppe

Department of Anesthesia, Deutsches Herzzentrum Berlin, Germany

Roland Hetzer

Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany

Over recent years, increasing awareness has been aroused to the hazards of the utilization of donor blood products. Particularly in neonate cardiac surgery employing cardiopulmonary bypass (CPB), the relative high priming volume of the CPB system and its adjunctive components, such as hemofilters, causes severe hemodilution and, therefore, particularly during extended perfusions, customarily requires priming of the system with autologous blood components. We report on our efforts to minimize the CPB system and adjust the perfusion strategy to the goal of transfusion-free CPB in a 3.7 kg neonate scheduled for repair of transposition of the great arteries.

Perfusion, Vol. 18, No. 6, 377-379 (2003)
DOI: 10.1191/0267659103pf686oa
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F. Merkle, W. Boettcher, F. Schulz, A. Koster, M. Huebler, and R. Hetzer
Perfusion technique for nonhaemic cardiopulmonary bypass prime in neonates and infants under 6 kg body weight
Perfusion, July 1, 2004; 19(4): 229 - 237.
[Abstract] [PDF]