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Perfusion, Vol. 18, No. 1 suppl, 75-80 (2003)
DOI: 10.1191/0267659103pf631oa

Blood cardioplegia filtration

Juergen Martin

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany, Martin{at}ch11.ukl.uni-freiburg.de

Matthias Krause

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany

Christoph Benk

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany

Georg Lutter

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany

Michael Siegenthaler

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany

Friedhelm Beyersdorf

Department of Cardiovascular Surgery, Albert-Ludwigs-University Medical Centre, Freiburg, Germany

The introduction of blood cardioplegia has been proven to limit ischaemia and reperfusion injury in cardiac surgery. But the presence of activated neutrophils in the capillary bed may cause further damage. Leukocyte filters have been shown to be very effective in reducing the leukocytes in blood cardioplegia to less than 10%. Leukocyte depletion of blood cardioplegia provides an excellent approach to minimizing myocardial injury, predominantly in high-risk cardiac surgery.


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