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Perfusion
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Subsystem organ function during coronary surgery

Raimondo Ascione

Bristol Heart Institute, University of Bristol, Bristol, UK

Sharif Al-Ruzzeh

Bristol Heart Institute, University of Bristol, Bristol, UK

Khalid Amer

Bristol Heart Institute, University of Bristol, Bristol, UK

Gianni D Angelini

Bristol Heart Institute, University of Bristol, Bristol, UK, g.d.angelini{at}bristol.ac.uk

Conventional coronary artery bypass grafting (CABG) carries a mortality rate of 1% to 2% in elective patients. However, despite advances in perfusion, anaesthetic, and surgical techniques cardiopulmonary bypass (CPB) is still associated with subsystem dysfunction. Off-pump coronary artery bypass grafting (OPCAB) has recently gained popularity as a potentially more physiological method to maintain the functional integrity of major organ systems. The review of observational reports, case-matched studies and prospective randomized trials seems to suggest that OPCAB surgery reduces postoperative subsystem organ dysfunction when compared with conventional coronary revascularisation.

Perfusion, Vol. 17, No. 4, 295-303 (2002)
DOI: 10.1191/0267659102pf583oa
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