Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Perfusion
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Miyashita, T.
Right arrow Articles by Kuro, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Miyashita, T.
Right arrow Articles by Kuro, M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Retrospective analysis of effect of low-dose aprotinin priming on allogeneic blood transfusion in repeated cardiac operations

Tetsuya Miyashita

Department of Anesthesiology, National Cardiovascular Center, Suita, Osaka, tetsuyam{at}hsp.ncvc.go.jp

Yukio Hayashi

Department of Anesthesiology, National Cardiovascular Center, Suita, Osaka

Yoshihiko Ohnishi

Department of Anesthesiology, National Cardiovascular Center, Suita, Osaka

Masakazu Kuro

Department of Anesthesiology, National Cardiovascular Center, Suita, Osaka

The objective of this retrospective study was to investigate efficacy of low-dose aprotinin priming therapy on the requirement of allogeneic transfusion and to identify risk factors for allogeneic transfusion in patients undergoing repeated cardiac operations.

The present study includes a critical review of 124 consecutive charts of patients undergoing elective repeat cardiac surgery. We examined the effect of low-dose aprotinin priming therapy on blood loss, amounts of mediastinal drainage following intensive care unit (ICU) administration and the number of units of blood products given during the perioperative period.

The rate of nonallogeneic transfusion was not affected by low-dose aprotinin priming therapy, although aprotinin reduced the amount of allogeneic transfusion and the amount of mediastinal drainage 12 h following ICU admission.

In conclusion, low-dose aprotinin priming therapy is effective in reducing blood loss and the amount of allogeneic transfusion. However, it failed to improve the rate of cardiac reoperations without allogeneic blood transfusion.

Perfusion, Vol. 14, No. 3, 189-194 (1999)
DOI: 10.1177/026765919901400306
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?